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Fig 1.

Recruitment flow-chart.

CAD: Coronary artery disease. NSTEACS: Non-ST elevation Acute Coronary Syndrome. STEMI: ST-elevation myocardial infarction.

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Table 1.

Characteristics of patients with and without cancer.

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Fig 2.

Box graphs showing data of the different analytical variables in patients with and without cancer.

Boxes represent the interquartile ranges, with a thick line inside representing the median value. Points outside boxes represent individual values that are not included in the interquartile range. CKD-EPI: Chronic Kidney Disease-Epidemiology Collaboration Method; GFR: Glomerular Filtration Rate; HDL: High-density lipoprotein; LDL: Low-density lipoprotein. NT-proBNP: N-terminal pro-brain natriuretic peptide; sTWEAK: soluble tumor necrosis factor-like weak inducer of apoptosis.

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Fig 3.

Linear regressions showing the correlations of NT-proBNP with age and other biomarkers studied.

Correlations were significant but mild with age, Glomerular Filtration Rate (GFR) as assessed by the Chronic Kidney Disease Epidemiology Collaboration Method (CKD-EPI), high-sensitivity C-reactive protein (hs-CRP), high-sensitivity cardiac troponin I (hs-cTnI), monocyte chemoattractant protein-1 (MCP-1), galectin-3 (Gal3), and triglyceride plasma levels. Log: Logarithm.

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Table 2.

Multivariate linear regression analysis showing the influence of other variables on N-terminal probrain natriuretic peptide levels.

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Table 2 Expand

Table 3.

Multivariate Cox regression analysis for the incidence of cancer, heart failure, or death.

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Table 3 Expand