Table 1.
Patient-Control Comparisons on Demographics, Diagnostic and Behavioral Measures.
Fig 1.
Whole brain VBM analyses: Controls>Patients.
The 3D color map showing various frontal and parietal regions where Controls>Patients. Color bar represents t-value.
Table 2.
Whole brain analysis results where female controls showed greater GM volumes than SCP female patients.
Fig 2.
GM volume details of ROI where Controls>Patients.
Nine panels which correspond to the clusters of Control>Patient GM volume demonstrated with whole-brain analyses. Each panel displays two histograms, salmon color bars indicating controls and teal color bars indicating patients. For all histograms, the x-axis represents GM volume (intensities mapping GM volume in mL) and the y-axis represents number of subjects.
Table 3.
ROIs where GM volumes in female controls exceeded GM volumes in SCP patients.
Fig 3.
Whole brain regression analyses with BD within patients.
Color map (Y coordinate: 25 mm) in Fig 3a showing negative association between the bilateral striatum and BD score in patients after co-varying for age and IQ. Color map (Y coordinate = -3 mm) in Fig 3b showing positive association between the insula and BD score in patients after co-varying for age and IQ. The crosshairs mark the voxel with maximum association and the regression plots below the color maps show the association between the region and BD score for that voxel with maximum association. A 95% confidence interval will contain the true parameter (slope) with probability 0.95. The prediction interval is an estimate of an interval in which future observations will fall, with probability 0.95, given what has already been observed. Rt = Right.
Fig 4.
Whole brain regression analyses with conduct disorder symptom count within patients.
Color map (Y coordinate: -25 mm) showing negative association between the left somatosensory and motor cortex region (i.e. precentral and postcentral gyrus (BA 1, 2, 3 and 4)) and supramarginal gyrus and inferior parietal lobule (BA 40)) and BD score in patients after co-varying for age and IQ. The crosshair marks the voxel with maximum association and the regression plots below the color map shows the association between the region and conduct disorder symptom count Z-score for that voxel with maximum association. Rt = Right.