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Fig 1.

Flow chart of study participants throughout the trial.

Of the 250 patients who were enrolled, 209 patients (azelnidipine group: 103 patients, trichlormethiazide group: 106 patients) completed the trial. Seventeen patients in the azelnidipine group and fourteen patients in the trichlormethiazide group were excluded because they were lost-to-follow-up or because of missing data.

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Fig 1 Expand

Table 1.

Baseline characteristics of the subjects.

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Table 1 Expand

Table 2.

Time courses for clinical parameters in the azelnidipine group and the trichlormethiazide group.

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Table 2 Expand

Table 3.

Changes in clinical parameters at 48 weeks relative to baseline values.

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Table 3 Expand

Table 4.

Changes in clinical parameters at 48 weeks relative to baseline values in per-protocol analyses.

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Table 4 Expand