Fig 1.
Tonotopic maps in the left and right hemisphere.
(LH, RH) of a typical subject in the lateral view of the hemispheres (FDR corrected: 0.05, r>0.20; top) and enlarged, in upper view of the unfolded STP (bottom). In each hemisphere, two mirror-symmetric gradients, corresponding to the primary areas A1 and R, are located on HG. The surrounding, frequency-selective region (p = 0.05, uncorrected) was subdivided into 8 ROIs: M1, L1, M2, L2, M3, L3, M4, and L4. Several ROIs were homologues of the auditory areas found in previous architectonic studies [5,6]. M1, L1, L2, L3, L4 and M4 corresponded, respectively, to PA (posterior auditory area), LA (lateral auditory area), ALA (anterior lateral auditory area), AA (anterior auditory area), ALA—AA (junction between ALA and AA), and MA (medial auditory area).
Table 1.
Mean Talaraich coordinates of all ROIs.
Fig 2.
Mean of the group average time-courses of the REP and CTRL conditions within the auditory cortex on the STP (defined by main effect of environmental sound) in the left and right hemisphere (LH, RH).
Significant differences between conditions are highlighted by the green bars in the bottom of the graphs (paired t-test, p<0.05, uncorrected). Gray shading denotes the rise and decay periods (for definition see Supporting Information).
Fig 3.
Group average time-courses of the two conditions in the left hemisphere within individual early-stage areas.
BOLD signal changes (in %) were plotted across time points of the block. REP blocks tended to yield lower activation than CTRL blocks. Significant differences between conditions and hemispheres are highlighted by green (CTRL > REP), red (CTRL LH > CTRL RH) and blue bars (REP RH > REP LH) at the bottom of each graph (paired t test, p<0.05, uncorrected).
Fig 4.
Group average time-courses of the two conditions in the right hemisphere within the auditory cortex ROIs.
BOLD signal changes (in %) were plotted across time points of the block. REP blocks tended to yield lower activation than CTRL blocks. Same conventions as in Fig 3.
Fig 5.
Time frame by time frame 2-way ANOVA condition (REP, CTRL) x hemisphere (RH, LH) for each of the 10 early stage areas (A1, R, L1, L2, L3, L4, M1, M2, M3, M4).
Gray shading highlights the rise and decay periods, red hues denote significant effects at a given time point and area. During the plateau phase a significant main effect of condition was present in A1, R, M1, M2, M3 and M4 as well as a significant main effect of hemisphere at isolated time points in M1 and M2.
Fig 6.
Early-stage auditory areas with repetition suppression effect, i. e. significant difference between the REP and CTRL conditions during the plateau phase (gray shading).