Fig 1.
Fundus photographs of eye with macular hole and fellow eye.
This case had macular hole in left eye (A and B). To mask the laterality of diseased eye, macular area of both eyes were covered by the square shield (C and D).
Fig 2.
Trajectories of retinal arteries.
The fundus photograph was rotated 90 degrees clockwise for the right eye and 90 degrees counterclockwise for the left eye (A and B). The retinal arteries were marked by at least 20 points. The coordinates of the marked spots were determined automatically using ImageJ software and converted to a new set of data with the center of the optic disc as the origin. The converted coordinate data were fit to a user-defined second degree polynomial equation (ax2/100 + bx + c) (C and D).
Table 1.
Patient demographics.
Fig 3.
Scatter plot of eyes with macular hole (MH) and fellow eyes.
The curve of retinal artery trajectory was expressed by a second degree polynomial equation, where a larger constant “a” made the curve steeper. Most of plots are distributed in the area above the diagonal line, indicating the “a” constant was significantly smaller in eyes with MH than fellow eyes (P = 0.001, paired t test).
Fig 4.
Axial length of macular hole eye and fellow eye (paired-eyes).
There was no significant difference in the axial lengths between the MH eyes and fellow eyes (P = 0.462).
Fig 5.
Scatterplots of the retinal artery trajectories and the axial lengths.
The retinal artery trajectory, expressed as “a” was significantly and positively correlated with the axial length in eyes with a macular hole (A) and the fellow eyes (B).
Fig 6.
Retinal artery (RA) trajectory and posterior vitreous detachment in fellow eyes.
The status of the posterior vitreous interface was classified according to Uchino et al [23]. There was no significant difference in the ‘a’ of the RA trajectory between any two of classifications including S0 and S4 (P = 0.370, Mann-Whitney U test).