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Table 1.

Clinical and laboratory patient characteristics.

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Table 2.

Regression coefficients (B), confidence intervals (CI), and p-values (p) of multivariate regression analyses of age, sex, body mass index (BMI), hypertension, hyperlipidemia, diabetes, active smoking, platelet count, white blood cell count (WBC), log transformed interleukin-6 (log IL-6),log transformed high-sensitivity C-reactive protein (log hsCRP), log transformed serum creatinine (log creatinine), and log transformed asymmetric dimethylarginine (log ADMA) for surface expression of P-selectin, activation of glycoprotein (GP) IIb/IIIa, and formation of monocyte-platelet aggregates (MPA).

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Fig 1.

Platelet surface expression of P-selectin and activated glycoprotein (GP) IIb/IIIa.

(A) Platelet surface expression of P-selectin in patients with high (>median) vs. low (≤median) interleukin (IL)-6 levels. (B) Platelet surface expression of activated GPIIb/IIIa in patients with high (>median) vs. low (≤median) asymmetric dimethylarginine (ADMA) levels. The boundaries of the box show the lower and upper quartile of data, the line inside the box represents the median. Whiskers are drawn from the edge of the box to the highest and lowest values that are outside the box but within 1.5 times the box length. MFI, mean fluorescence intensity.

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Table 3.

Regression coefficients (B), confidence intervals (CI), and p-values (p) of multivariate regression analysis of age, sex, body mass index (BMI), hypertension, hyperlipidemia, diabetes, active smoking, platelet count, white blood cell count (WBC), and log transformed serum creatinine (log creatinine) for high interleukin-6 levels (high IL-6) and high asymmetric dimethylarginine (high ADMA).

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Table 3 Expand