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Table 1.

Studies excluded from this review.

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Table 2.

General characteristics of the included studies.

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Fig 1.

Flow chart shows the process of article selection for this study.

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Table 3.

Demographic and clinical characteristics (Total patients = 107).

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Fig 2.

Comparison of overall survival rate in local disease and metastatic disease.

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Fig 3.

Compared with non-axial region, tumor in axial region has a much lower overall survival rate (p = 0.027).

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Fig 4.

Prognostic significance of age of the patients is shown.

It is comparison of patients elder than 30 and those younger than 30.

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Fig 5.

This figure shows the comparison of overall survival for patients treated with surgery and those without.

A statistically significant difference was noted between the groups by the COX regression test (p = 0.000).

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Fig 6.

This figure shows the comparison of overall survival for patients treated with chemotherapy and those without.

There was a trend for patients to get a better overall survival with chemotherapy, however with no statistically significany.

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Fig 7.

Local-recurrence-free survival of these 82 patients was estimated using the Kaplan-Meier plots.

(A) A statistically significant difference was noted between the positive margins and negative margins by COX regression (p = 0.000). (B) For positive margins, postoperative radiation therapy could remarkably bring down local recurrence rate(p = 0.013).

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Table 4.

Studies (N>10) of MCS published 20 years ago.

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