Table 1.
Morphological features of different types of tumor cells in CSF specimens (n = 78, samples from all 80 LM patients had positive CSF results except two patients with unknown primary tumors).
Fig 1.
Different pathological types of tumor cells detected in CSF specimens.
a-n, adenocarcinoma cells; o-q, cancerous squamous cells; r-s, small-cell lung cancer cells; t-u, hepatocellular carcinoma cells; v-x, large-cell lung cancer cells; y-z, malignant melanoma cells. (Thinprep, Pap staining, ×400)
Fig 2.
Side-by-side comparisons of CSF cytology results between the Thinprep plus Papanicolaou stain method (a, c, e, g, i and k) and the Cytospin-WG method (b, d, f, h, j and l) in patients with LM from various solid tumors.
Representative slides from identical CSF samples are shown for the same samples using the two methods in paired photos: a and b, gastric adenocarcinoma origin; c-h, lung adenocarcinoma origin; i and j breast adenocarcinoma origin; k and l, small-cell lung cancer origin. m-p, the typical features of malignancy of tumor cells seen by the Cytospin- WG stain method.