Table 1.
Diagnostic Codes Defined as Acute Bronchiolitis, Other Acute Airway Infections and Asthma of the Enrolled Children.
a
Fig 1.
Flow chart of case enrollment from the National Health Insurance Research Database in Taiwan.
LHID 2010, Longitudinal Health Insurance Database with random sampling of beneficiaries enrolled in 2010.
Table 2.
Characteristics of the children at enrollment and onset of childhood asthma at age 3 to 10 years.
Fig 2.
Age distribution of childhood asthma at 3–10 years in children with/without early hospitalized airway infections.
Fig 3.
Cumulative asthma event-free rates of the enrolled children aged 3 to 10 years in different groups.
Kaplan-Meier survival analysis was performed. p < 0.001 by the log rank test; p < 0.001 by the Breslow test; p < 0.001 by the Tarone-Ware test.
Table 3.
Adjusted odds ratios of children with early hospitalized airway infections (HAIs) (< 3 years) and childhood asthma (3–10 years), and those with combined comorbidities of preterm birth, congenital heart disease, or congenital respiratory diseases compared to the control group.
Table 4.
Subsequent hospitalization and ambulatory visit frequencies and expenses in the enrolled children at age 3 to 10 years.