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Fig 1.

Optimized structures of 7 compounds with orthodiphenolic functionalities calculated at the B3LYP/6-311++G(d,p) level in ethanol.

(left: a hydrogen bond is formed between the 4-O center and the meta OH. right: no hydrogen bond is formed between the 4-O center and the meta OH.)

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Fig 1 Expand

Fig 2.

The energy difference (ΔE in kcal/mol) caused by the hydrogen bond between the O center and the meta OH for 7 radicals calculated at the B3LYP/6-311++G(d,p) levels of theory in 4 reaction media.

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Fig 2 Expand

Table 1.

BDEs of 20 investigated phenolic compounds and phenol calculated at the B3LYP/6-311++G(d,p) level a.

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Table 1 Expand

Fig 3.

Spin density values of phenoxy radicals of 20 investigated phenolic compounds and phenol calculated at the B3LYP/6-311++G(d,p) levels of theory in ethanol.

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Fig 3 Expand

Table 2.

Absolute (E in kcal/mol) and relative energies (ΔE in kcal/mol) of various hydrogen atom-abstracted radicals in 4 reaction environments calculated at the B3LYP/6-311++G(d, p) levels of theorya.

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Table 2 Expand

Table 3.

IPs and PDEs of 20 investigated phenolic compounds and phenol calculated at the B3LYP/6-311++G(d,p) level a.

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Table 3 Expand

Table 4.

PAs and ETEs of 20 investigated phenolic compounds and phenol calculated at the B3LYP/6-311++G(d,p) level a.

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Table 4 Expand

Fig 4.

HOMO of 20 investigated phenolic compounds calculated at the B3LYP/6-311++G(d,p) levels of theory in ethanol.

The numbers indicates atomic polar tensor charges.

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Fig 4 Expand

Table 5.

QSAR modeling results of the thermodynamics-activity relationship for 20 phenolic compounds in water and ethanol a.

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Table 5 Expand