Table 1.
Characteristics of studies included in the meta-analysis.
Fig 1.
Flow diagram of included studies.
Fig 2.
Forest plot of risk ratios for total number of patients with one or more exacerbations treated with macrolides compared with the control.
Fig 3.
Forest plot of risk ratios for exacerbations per patient per year treated with macrolides compared with the control.
Table 2.
Subgroup analyses of prophylactic macrolide treatment on the prevention of acute exacerbations of COPD.
Fig 4.
Forest plot assessing risk ratio of hospitalization among COPD patients treated with macrolides compared with the control.
Fig 5.
Forest plot of comparing the mean differences (MD) in change of SGRQ total score among COPD patients treated with macrolides compared with the control.
Fig 6.
Forest plot of odds ratios for drug adverse effects in COPD patients treated with macrolides compared with the control.