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Fig 1.

The corpus callosum used to calculate the FWHM.

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Fig 2.

The relationship between the SNR and the b-value.

(a) The SNR of corpus callosum. (b) The SNR of centrum semiovale.

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Fig 3.

The FWHM of the diffusion ODF from S1 at five b-values.

(a) Distribution of the diffusion ODF measured by SPFI for S1 at five b-values. The x-axis shows the colatitudes, where 0° indicates that the orientation is parallel to that of the principal direction. (b) The FWHM of the ODF profile measured in (a). (*) indicates statistically significant differences between groups (p < 0.001).

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Fig 4.

The group FWHM of the diffusion ODF from all eight subjects at five b-values.

(*) indicates statistically significant differences between groups (p < 0.001).

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Fig 5.

The FWHM of the fiber ODF from S1 at five b-values.

(a) Distribution of the fiber ODF measured by CSD for S1 at five b-values. The x-axis shows the colatitudes, where 0° indicates that the orientation is parallel to that of the principal direction. (b) The FWHM of the ODF profile measured in (a). (*) indicates statistically significant differences between groups (p < 0.001).

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Fig 6.

The group FWHM of the fiber ODF from all eight subjects at five b-values.

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Fig 7.

The angular difference in the diffusion ODF obtained with SPFI between each pair of neighboring b-values.

(a) The angular difference for one-directional situations. (b) The angular difference for two-directional situations.

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Fig 8.

The angular difference in the diffusion ODF obtained with SPFI between each pair of b-values.

(a) The angular difference for one-directional situations.(b) the angular difference for two-directional situations. The color in the grid indicates the angular difference in the ODF between the two b-values in the x-axis and the y-axis.

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Fig 9.

The angular difference in the fiber ODF obtained with CSD between each pair of neighboring b-values.

(a) The angular difference for one-directional situations. (b) The angular difference for two-directional situations.

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Fig 9 Expand

Fig 10.

The angular difference in the fiber ODF obtained with CSD between each pair of b-values.

(a) The angular difference for one-directional situations. (b) The angular difference for two-directional situations. The color in the grid indicates the angular difference in the ODF between the two b-values in the x-axis and the y-axis.

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Fig 10 Expand

Fig 11.

The diffusion ODFs of the DWI data from different b-values in the centrum semiovale.

The b-values for (A)-(E) were 650, 1000, 1500, 2000, 2500 s/mm2, respectively. The top-left figure indicates the centrum semiovale by a red rectangle. The three specially marked voxels in (a)-(c) are given a closer look in Fig. 12.

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Fig 12.

The diffusion ODFs of three voxels (those marked in Fig. 11A-C) at different b-values.

The three voxels contain different numbers of fiber directions. Each row illustrates the ODFs of the same voxel at different b-values. The yellow sticks represent the principal peak(s) of the ODFs.

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Fig 13.

The fiber ODFs of the DWI data from different b-values in the centrum semiovale.

The b-values of (A)-(E) = 650, 1000, 1500, 2000, 2500 s/mm2, respectively. The top-left figure indicates the centrum semiovale by a red rectangle. The three specially marked voxels in (a)-(c) are given a closer look in Fig. 14.

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Fig 14.

The fiber ODFs of three voxels (also marked in Fig. 13A-C) at different b-values.

The three voxels contain different numbers of fiber directions. Each row illustrates the ODFs of the same voxel at different b-values. The yellow sticks represent the principal peak(s) of the ODFs.

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Fig 14 Expand