Fig 1.
Axial image of a Multiple Sclerosis patient.
(A) Proton density-weighted image; (B) T2-weighted image; (C) corresponding multiparametric image; (D) segmented image. In the segmented image, white matter is represented by white, gray matter by gray, cerebrospinal fluid by blue, and lesions by yellow.
Table 1.
Demographic, clinical characteristics, *adjusted baseline MRI volume (as percentage of whole brain volume) and **neuropsychological test scores of MS patients (mean ± SD).
Table 2.
Univariable analysis verbal memory, sustained attention/information processing speed, executive function/conceptual reasoning.
Table 3.
Multivariate analysis verbal memory, sustained attention/information processing speed, executive function/conceptual reasoning.
Fig 2.
Proportion of RRMS and SPMS patients with impaired performance at each test.
Legend: RRMS = relapsing-remitting multiple sclerosis, SPMS = secondary progressive multiple sclerosis, SDMT = symbol digit modality test, PASAT-3 = 3.0 inter-stimulus interval of Paced Auditory Serial Addition Test, SRWL = semantically related word list test, IR = immediate recall, DR = delayed recall, REC = recognition, MCST CAT = modified card sorting test categories, MCST-PE = MCST perseverative errors, MCST-NPE = MCST non-perseverative errors.