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Table 1.

Quality assessment standard for a cross-over study.

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Fig 1.

Flow chart for selection of studies.

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Fig 2.

Summary of the quality assessment of the 139 cross-over trials

1. Appropriate cross-over design; 2. Randomized order of receiving treatment; 3. Carry-over effects; 4. Unbiased data; 5. Allocation concealment; 6. Blinding; 7. Incomplete outcome data; 8. Selective outcome reporting; 9. Other bias

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Table 2.

The results of quality reassessment of different items.

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Table 2 Expand