Table 1.
Body weight changes (mean ± standard deviation) in male and female rats before and after Ah administration.
Table 2.
Hematological parameters (mean ± standard deviation) in male rats intragastrically administered Ah daily for 14 consecutive days.
Table 3.
Hematological parameters (mean ± standard deviation) in female rats intragastrically administered Ah daily for 14 consecutive days.
Table 4.
Biochemical parameters (mean ± standard deviation) in male rats intragastrically administered Ah daily for 14 consecutive days.
Table 5.
Biochemical parameters (mean ± standard deviation) in female rats intragastrically administered Ah daily for 14 consecutive days.
Table 6.
Relative organ weight (mean±standard deviation) in males intragastrically administered Ah daily for 14 consecutive days.
Table 7.
Relative organ weights (mean ± standard deviation) in female rats intragastrically administered Ah daily for 14 consecutive days.
Table 8.
Histopathological findings for male rats treated with Ah for 14 days.
Table 9.
Histopathological findings for female rats treated with Ah for 14 days.
Fig 1.
Photomicrograph of duodenum tissue of control group stained with HE.
There is no abnormal.
Fig 2.
Photomicrograph of duodenum tissue of low dose group stained with HE.
There is no abnormal.
Fig 3.
Photomicrograph of duodenum tissue of medium dose group stained with HE.
A:Acute catarrhal enteritis with eosinophilic infiltration; C: Goblet cell hyperplasia; D: Congestion in the lamina propria.
Fig 4.
Photomicrograph of duodenum tissue of high dose group stained with HE.
A:Acute catarrhal enteritis with eosinophilic infiltration; B:Degeneration, necrosis and exfoliation of intestinal epithelial cells; C: Goblet cell hyperplasia.
Fig 5.
Photomicrograph of spleen tissue of control group stained with HE.
There is no abnormal.
Fig 6.
Photomicrograph of spleen tissue of low dose group stained with HE.
There is no abnormal.
Fig 7.
Photomicrograph of spleen tissue of medium dose group stained with HE.
A: Passive congestion.
Fig 8.
Photomicrograph of spleen tissue of high dose group stained with HE.
A: Passive congestion; B: Edema.
Fig 9.
Photomicrograph of kidney tissue of control group stained with HE.
There is no abnormal.
Fig 10.
Photomicrograph of kidney tissue of low dose group stained with HE.
There is no abnormal.
Fig 11.
Photomicrograph of kidney tissue of medium dose group stained with HE.
C: Congestion.
Fig 12.
Photomicrograph of kidney tissue of high dose group stained with HE.
A: Granular degeneration in renal tubular epithelial cells; B:Focalnecrosis.
Fig 13.
Photomicrograph of liver tissue of control group stained with HE.
There is no abnormal.
Fig 14.
Photomicrograph of liver tissue of low dose group stained with HE.
There is no abnormal.
Fig 15.
Photomicrograph of liver tissue of medium dose group stained with HE.
A:Granular degeneration of liver cells; B:Congestion.
Fig 16.
Photomicrograph of liver tissue of high dose group stained with HE.
A:Granular degeneration of liver cells; B:Congestion.
Fig 17.
Photomicrograph of heart tissue of control group stained with HE.
There is no abnormal.
Fig 18.
Photomicrograph of heart tissue of low dose group stained with HE.
There is no abnormal.
Fig 19.
Photomicrograph of heart tissue of medium dose group stained with HE.
A:Interstitial hydrops; D: Myocardial necrosis.
Fig 20.
Photomicrograph of heart tissue of high dose group stained with HE.
A:Interstitial hydrops; B: Congestion; C:Myocardial degeneration D: Myocardial necrosis.
Fig 21.
Photomicrograph of brain tissue of control group stained with HE.
There is no abnormal.
Fig 22.
Photomicrograph of brain tissue of low dose group stained with HE.
There is no abnormal.
Fig 23.
Photomicrograph of brain tissue of medium dose group stained with HE.
A: Edema; B: Coagulative necrosis.
Fig 24.
Photomicrograph of brain tissue of high dose group stained with HE.
A: Edema; B: Coagulative necrosis; C: Congestion.