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Fig 1.

Flow diagram of the study selection process.

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Table 1.

Main characteristics of enrolled studies.

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Table 2.

Main results of enrolled studies.

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Fig 2.

Forest plots of the relationship between elevated miR-21 level and OS (A) and DFS/RFS (B).

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Table 3.

Subgroup analyses of pooled hazard ratios for overall survival with elevated miR-21 expression.

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Table 4.

Meta-analyses of miR-21 Expression Classified by clinicopathologic parameters.

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Fig 3.

Funnel plot for publication bias analysis: (A) OS; (B) DFS/RFS.

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Fig 4.

Sensitivity analysis for OS (A) and DFS/RFS (B).

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