Fig 1.
Neonatal (A) and adult (B) landmarks used in this study.
Landmark descriptions and numbers are provided in Table 1.
Table 1.
Landmark information including: descriptions, whether they were taken on adults or neonates or both, and their assigned modules.
Table 2.
Procrustes distances between neonatal mean shapes.
Table 3.
Procrustes distances between adult mean shapes.
Fig 2.
Principal components analysis (PCA) of neonatal mouse skulls.
A) Scatter plot of PC1 and PC2 of neonatal whole-skull shape. B) Wireframe depictions of group mean shapes. Abbreviations: PC = principal component; OG = Pten overgrowth model; OGc = overgrowth control, UG1 = Trsp undergrowth model; UG1c = Trsp undergrowth control. See Materials and Methods for a full explanation of these models.
Fig 3.
Principal components analysis (PCA) of adult mouse skulls.
A) Scatter plot of PC1 and PC2 of adult whole-skull shape. B) Wireframe depictions of group mean shapes. Abbreviations: PC = principal component; OG = Pten overgrowth model; OGc = overgrowth control, UG1 = Trsp undergrowth model; UG1c = Trsp undergrowth control; UG2 = Brachymorph undergrowth model; UG2c = brachymorph undergrowth control. See Materials and Methods for a full explanation of these models.
Fig 4.
Two-block partial least squares analysis (PLS) of the neonatal mouse basicranium and face.
Wireframes depict singular warp deformations of shape along each PLS axis. Abbreviations: PLS = partial least squares axis; OG = Pten overgrowth model; OGc = overgrowth control, UG1 = Trsp undergrowth model; UG1c = Trsp undergrowth control. See Materials and Methods for a full explanation of these models. Wireframe superimposition on skull renderings indicates approximate position of landmarks under consideration.
Table 4.
Covariation hypothesis testing results for the neonatal sample.
Fig 5.
Two-block partial least squares analysis (PLS) of the neonatal mouse basicranium and calvarium.
Wireframes depict singular warp deformations of shape along each PLS axis. Abbreviations: PLS = partial least squares axis; OG = Pten overgrowth model; OGc = overgrowth control, UG1 = Trsp undergrowth model; UG1c = Trsp undergrowth control. See Materials and Methods for a full explanation of these models. Wireframe superimposition on skull renderings indicates approximate position of landmarks under consideration.
Fig 6.
Two-block partial least squares analysis (PLS) of the adult mouse basicranium and face.
Abbreviations: PC = principal component; OG = Pten overgrowth model; OGc = overgrowth control, UG1 = Trsp undergrowth model; UG1c = Trsp undergrowth control; UG2 = Brachymorph undergrowth model; UG2c = brachymorph undergrowth control. See Materials and Methods for a full explanation of these models. Wireframe superimposition on skull renderings indicates approximate position of landmarks under consideration.
Table 5.
Covariation hypothesis testing results for the adult sample.
Fig 7.
Two-block partial least squares analysis (PLS) of the adult mouse basicranium and calvarium.
Abbreviations: PC = principal component; OG = Pten overgrowth model; OGc = overgrowth control, UG1 = Trsp undergrowth model; UG1c = Trsp undergrowth control; UG2 = Brachymorph undergrowth model; UG2c = brachymorph undergrowth control. See Materials and Methods for a full explanation of these models. Wireframe superimposition on skull renderings indicates approximate position of landmarks under consideration.