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Fig 1.

Morphology of S. porticalis under Leica DM500 research microscope.

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Table 1.

Antioxidant capacities of S. porticalis extractsa.

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Table 2.

Total phenolic (TPC), flavanoid (TFC) and proanthocyanidin content (TPAC) in S. porticalis extracts from Indian trans-Himalayaa.

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Fig 2.

GC/MS chemometric profile of S. porticalis methanol extract.

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Table 3.

Algal chemotypes identified in methanol extract of S. porticalis by GC/MS.

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Fig 3.

Cytotoxic effect of S. porticalis methanol extract on HepG2 and RKO cells.

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Table 4.

Cytotoxicity of methanol extract of S. porticalis against HepG2 and RKO cells.

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Fig 4.

Microscopic images (10×10X) showing cell growth and morphology after 24 h treatment of S. porticalis extract in HepG2 and RKO cancer cells.

a. HepG2 cells with good growth, b. HepG2 cells with partially arrested or 50% arrested growth, c. HepG2 cells with arrested growth, d. HepG2 dead cells, e. RKO cells with good growth, f. RKO cells with partially arrested or 50% arrested growth, g. RKO cells with arrested growth, h. RKO dead cells.

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Fig 5.

Changes in serum GSH, GSSG, GSH/GSSG and ROS level following administration of S. porticalis methanol extract during exposure to hypobaric hypoxia.

a. Changes in reduced glutathione level, b. Changes in the level of oxidised glutathione, c. Changes in GSH/GSSG level, d. Changes in reactive oxygen species generation. * denotes p≤0.05 when compared to normoxia, # denotes p≤0.05 when compared to normoxia + vehicle, $ denotes p≤0.05 when compared to hypoxia + vehicle.

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