Table 1.
ASL-assessed patients’ and controls’ demographic data and cause of injury.
Fig 1.
Diagram of the ASL analysis workflow.
T2 images were skull-stripped and normalized to the ICBM T1-weighted template. A transformation matrix was applied to skull-stripped rCBF images with SPM8, to bring them into the same template. ROIs were selected automatically in the lobes and in deep brain structures using the Wake Forest University (WFU) PickAtlas.
Fig 2.
Major veins selected for susceptibility analysis.
1) Left spetal vein; 2) right septal vein; 3) central septal veins; 4) left thalamostriate vein; 5) right thalamostriate vein; 6) internal cerebral vein; 7) left basal vein of Rosenthal; and 8) right basal vein of Rosenthal.
Fig 3.
Mean susceptibility values and standard error in major veins.
* indicates statistically significant difference between controls and acute visit; † indicates statistically significant difference between acute visit and one-month follow up. R: right, L: left, Int: internal.
Table 2.
Group mean values for each vein and student’s T-test comparison between control & patient groups and between control and follow-up groups.
Fig 4.
Mean regional rCBF in the thalamus and striatum and cortical lobes of control and patient groups, with standard error bars.
* p < 0.05.
Table 3.
Comparison of mean CBF values (in mL/100g/min) between control and patient groups.
Fig 5.
Group differences in SAC scores between controls and mTBI patients.
* p < 0.05.
Table 4.
mTBI patients' SAC scores compared with normalized SAC scores.