Fig 1.
Flow diagram of the literature search process.
Table 1.
Clinicopathological and methodological features of eligible studies.
Table 2.
Meta-analyses estimating the relevance of survivin with regard to clinicopathological variables.
Fig 2.
Funnel plots assessing possible publication bias for clinicopathological features (A: lymph node involvement; B: clinical stage; C: cell differentiation; D: depth of invasion; E: gender; F: age).
Fig 3.
Sensitivity analysis for clinicopathological features (A: lymph node involvement; B: clinical stage; C: cell differentiation; D: depth of invasion; E: gender; F: age).
Fig 4.
Forest plot estimating prognosis of patients with OSCC.
Fig 5.
Funnel plot and sensitivity analysis for prognosis of patients with OSCC (A: Funnel plot; B: sensitivity analysis).
Fig 6.
The information size to demonstrate the relevance of survivin protein expression with lymph node metastasis.
The dashed curve represents the cumulative Z-curve. The solid line represents the trial sequential monitoring boundary.