Figure 1.
CGM: continuous glucose monitoring. IGM: intermittent glucose monitoring.
Table 1.
Characteristics of the 48 very low birth weight newborns with intermittent (IGM) or continuous glucose monitoring (CGM).
Figure 2.
Number of hypoglycemic episodes per patient in the IGM-group and examples of hypoglycemic episodes.
Number of hypoglycemic episodes per patient detected by capillary blood glucose testing or continuous glucose monitoring in the IGM-group (A) and examples of hypoglycemic episodes (B and C). In 21 patients from the IGM-group, glucose level was monitored by capillary blood glucose testing performed every 4 hours and by blind continuous glucose monitoring system (CGMS, Guardian Clinical, Medtronic) that was analyzed retrospectively. Hypoglycemia was defined by a glucose level ≤50mg/dL. Number of hypoglycemia episodes per patient are expressed as mean ± SE; **p<0.01. In the first example (B), blind continuous glucose monitoring detected a hypoglycemic episode 100 min before capillary blood glucose testing. In the second example (C), hypoglycemic episode (90 min of duration) was detected solely by continuous glucose monitoring.
Figure 3.
Comparison between IGM- and CGM-group: number of heel pricks, number and duration of hypoglycemic episodes per patient.
Number of heel pricks per patient for capillary blood glucose testing (A), number (B) and duration (C) of hypoglycemic episodes per patient. Results are expressed as mean ± SE (A and B) or as median, 25% and 75% percentiles (box) and extreme values (whisker) (C) *p<0.05, ***p<0.001.
Figure 4.
Daily carbohydrate supplies in IGM- and CGM-group.
Results, expressed as mean ± SE, represent daily carbohydrate supplies during the first 4 days of life in IGM versus CGM-group (A), and in patients with (HYPO) versus without (NORMO) hypoglycemia in each group (B and C); *p<0.05.