Table 1.
Baseline characteristics of our 69 OHSCC patients.
Figure 1.
Kaplan-Meier estimates of neck control rates stratified according to hemoglobin level, ADC, and Ve values.
Figure 2.
Neck control in a 53-year-old male patient with right tonsillar oropharyngeal SCC after chemoradiation.
The patient’s hemoglobin level was 15.9 g/dL. A. Pretreatment axial-enhanced MRI identified a right cervical metastatic node (arrow). B. The corresponding ADC map showed a nodal ADC value of 0.78×10−3 mm2/s. C. The corresponding PWI map showed a nodal Ve value of 0.34. D. Post-treatment axial-enhanced MRI demonstrated a complete regression of the right metastatic node. A 15-month clinical and imaging follow-up did not disclose any nodal recurrence.
Figure 3.
Neck failure in a 45-year-old male patient with right hypopharyngeal SCC after chemoradiation.
The patient’s hemoglobin level was 12.7 g/dL. A. Pretreatment axial-enhanced MRI identified a right cervical metastatic node (arrow). B. The corresponding ADC map showed a nodal ADC value of 1.24×10−3 mm2/s. C. The corresponding PWI map showed a nodal Ve value of 0.07. D. Post-treatment axial-enhanced MRI demonstrated a residual right cervical node (arrow), which was further confirmed by neck dissection.
Table 2.
Univariate and multivariate analyses of 3-year neck control rates in OHSCC patients (n = 69).
Figure 4.
Kaplan-Meier estimates of 3-year neck control rates and overall survival in OHSCC patients according to the prognostic scoring system with combination of pretreatment hemoglobin level, ADC, and Ve values.
Table 3.
Multivariate analyses of 3-year neck control and overall survival rates according to the prognostic scoring system based on hemoglobin levels, Ve, and ADC.
Figure 5.
A. Kaplan-Meier estimates of neck control rates stratified according to the presence of local failure. B and C, Kaplan-Meier estimates of 3-year neck control rates and overall survival in OHSCC patients according to the prognostic scoring system based on pretreatment hemoglobin level, ADC, Ve values, and posttreatment local control status.