Fig 1.
Flow of Patients from enrollment to the end of study.
Table 1.
Comparison of the baseline data between the control (placebo) group and Nigella sativa group.
Table 2.
Changes in Fasting blood glucose (FBG), Hemoglobin A1c (HbA1c), C- peptide (C-pept), Insulin resistance (IR) and β-cell activity at different treatment durations, compared to their corresponding baseline values, in the control (placebo) and N. sativa groups.
Fig 2.
Changes in Fasting blood glucose (Mean±SEM) measured by self- monitoring glucometers, in the control (placebo) group and N. sativa group, compared to the corresponding baseline values using linear mixed model.
Difference is significant at * P < 0.05, ** P <0.01 and *** P < 0.001.
Fig 3.
Changes in Random blood glucose (Mean±SEM) measured by self- monitoring glucometers, in the control (placebo) group and N. sativa group, compared to the corresponding baseline values using linear mixed model.
Difference is significant at * P < 0.05, ** P <0.01 and *** P < 0.001.
Table 3.
Comparison of glycemic variables; fasting blood glucose (FBG), hemoglobinA1c (HbA1c), C- peptide, insulin resistance, and β-cell activity between the control (placebo) group and N. sativa group at different treatment durations.
Table 4.
Changes in Total antioxidants capacity (TAC), Superoxide dismutase (SOD) activity, Catalase (CAT) activity, Glutathione and Thiobarbituric acid reactive substances (TBARS) at different treatment durations, in control (placebo) group and N. sativa group, compared to their corresponding baseline values.
Table 5.
Comparison of Total antioxidant (TAC) capacity, antioxidant enzymes; super oxide dismutase activity (SOD), catalase (CAT) activity, glutathione level and lipid peroxidation index (thiobarbituric acid reactive substances TBARS) between the control (placebo) group and N. sativa group at different treatment durations.