Figure 1.
Poikilocytes in blood smears from rabbits.
(A) Acanthocytes (arrows) in a healthy rabbit; (B) echinocytes in a rabbit with renal failure; (C) schistocytes (closed arrowheads) in a rabbit with a dental abscess; and (D) spherocytes (open arrowhead) and schistocytes (open arrows) in a rabbit with a mandibular abscess. Wright-Giemsa stain. Scale bar = 10 µm.
Figure 2.
Prevalence of poikilocytes in 492 rabbits.
Fragmented cells include schistocytes, keratocytes, microcytes, and spherocytes.
Figure 3.
Dot plots of % poikilocytes in samples from healthy (n = 79) and diseased (n = 403) rabbits.
Significant differences between healthy and diseased rabbits were observed for % schistocytes, % keratocytes, % microcytes, and % total fragmented cells (P<.05, Wilcoxon).
Table 1.
Primary diagnosis by organ system for the 482 rabbits in the study (1990 to 2010).
Table 2.
The proportion of rabbits with specific diseases having moderate to marked acanthocytosis or echinocytosis and mild to moderate fragmentation as compared with healthy rabbits.
Table 3.
Hematologic and biochemical values (mean ± SEM) in 482 rabbits based on severity of poikilocytosis.
Figure 4.
Principal component analysis of % poikilocytes and selected laboratory values.
Two primary components were identified, in the right upper (component 2) and right lower (component 1) quadrants. The longer the arrow, the stronger the correlation. Analytes in left quadrants are negatively correlated with those in the diagonal quadrant.