Figure 1.
Optic nerve head quantitative parameters measured with enhanced depth imaging optical coherence tomography (OCT).
A radial OCT scans at the optic disc were obtained. White arrowheads show Bruch's membrane opening (BMO). Dotted line shows BMO reference plane. Black arrowhead shows the anterior surface of the lamina cribrosa (LC). The distance between BMO reference plane and anterior LC (α), prelamina tissue thickness (β) at the center of BMO reference plane, and the diameters of the BMOs (γ) are also indicated.
Table 1.
Baseline Patient Characteristics.
Figure 2.
Representative case of eye with glaucoma.
A fundus photograph (A) shows a glaucomatous disc with enlarged optic disc cupping and upper rim loss. A vertical OCT scan (B) shows a distance of 406 µm between Bruch's membrane opening reference line and the anterior lamina cribrosa (α). A circular OCT (C) scan shows thinning of the circumpapillary retinal nerve fiber layer (58 µm).
Figure 3.
Representative case of eye with compressive optic neuropathy caused by a meningioma.
A fundus photograph (A) shows optic nerve atrophy with pallor and enlarged optic disc cupping. A vertical OCT (B) scan shows a distance of 165 µm between Bruch's membrane opening reference line and the anterior lamina cribrosa (α). A circular OCT (C) scan shows severe thinning of the circumpapillary retinal nerve fiber layer (33 µm).
Table 2.
Comparison of OCT and HRT parameters among CON, glaucoma, and normal subjects.
Table 3.
Comparison of OCT and HRT parameters between eyes with CON with a glaucoma-like disc and eyes with glaucoma.
Table 4.
Diagnostic accuracy determined by computing the AUROCs, best sensitivity-specificity balance, likelihood ratios, and sensitivity at the fixed specificities for the optic nerve head parameters of OCT and HRT to discriminate between CON eyes with a glaucoma-like disc and glaucoma eyes.