Figure 1.
Study-flow diagram of included patients.
Table 1.
Patient characteristics at inclusion.
Figure 2.
Changes in left ventricular function according to levels of IL-8 in patients with ST-elevation myocardial infarction developing symptomatic heart failure.
Changes in wall motion score index from inclusion (median 22 h, interquartile range 14, 29 after PCI) to 6 weeks. Patients (n = 52) were dichotomized into groups according to a level of IL-8 at inclusion below (10.0−≤25.6 pg/mL) or above (25.7–209 pg/mL) median value. Data are presented as median values with interquartile range.
Table 2.
Patient characteristics at inclusion, stratified to levels of IL-8 ≤ or > median value.
Figure 3.
Temporal profiles of circulating inflammatory markers in patients with ST-elevation myocardial infarction developing symptomatic heart failure.
Levels of IL-6 (A), CRP (B), sIL-6R (C) and sgp130 (D), during the first 6 weeks after inclusion (median 22 h, interquartile range 14, 29, after PCI), (n = 61). Inset: The results according to randomization groups, levosimendan (n = 30) or placebo (n = 31). Median values with interquartile range. * Change from baseline, p<0.05 ** Change from baseline, p<0.001.
Figure 4.
Temporal profiles of circulating inflammatory markers in patients with ST-elevation myocardial infarction developing symptomatic heart failure.
Levels of MCP-1 (A), IL-8 (B), MMP-9 (C), sVCAM-1 (D), sICAM-1 (E) and TNF-α (F) during the first 6 weeks after inclusion (median time 22 h, interquartile range 14, 29, after PCI), (n = 61). Inset: The results according to randomization groups, levosimendan (n = 30) or placebo (n = 31). Median values with interquartile range. * Change from baseline, p<0.05 ** Change from baseline, p<0.001.