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Figure 1.

Mean weight of participants attending or missing the next visit.

Some patients return after a missed visit. Therefore no change in number of patients at week 28 and 32.

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Figure 1 Expand

Figure 2.

Analysis of difference in weight loss between placebo and topiramate pooled (96 and 192 mg/day) from baseline to week 60 using different methods.

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Figure 2 Expand

Figure 3.

Analysis of weight loss over time in topiramate pooled (96 or 192 mg/day) group using different imputation methods.

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Figure 4.

Analysis of weight loss over time in the placebo group using different imputation methods.

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Table 1.

Percentage weight change from enrolment (- 8 week) to end of treatment (week 60).

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Table 1 Expand