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Table 1.

Patient and tumor characteristics.

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Table 2.

Antibodys used in this study.

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Table 3.

Scoring System.

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Figure 1.

CD8+ T-cells: Location.

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Figure 2.

CD8+ T-cells infiltrating tumor tissue.

Microscope: Carl Zeiss, Jena, Germany, 20-fold magnification, room temperature, Adobe Photoshop.

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Figure 3.

CD8+ T-cells: Tumor infiltration pattern.

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Table 4.

Amount of cells.

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Figure 4.

FoxP3+ cells mainly accumulate centrally.

Carl Zeiss, Jena, Germany, 20-fold magnification, room temperature, Adobe Photoshop.

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Figure 5.

FoxP3+ cells: Location.

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Figure 6.

FoxP3+ cells: Tumor infiltration pattern.

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Table 5.

Localisation of cells.

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Table 6.

Tumor infiltration of cells.

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Table 7.

Biomarkers and their influence on overall survival.

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Figure 7.

Log-Rank-Test CD8+.

Central accumulation of CD8+ T cells is significally associated with survival (p = 0.049).

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Figure 8.

Log-Rank-Test FoxP3+.

Peripheral accumulation of FoxP3+ Cells leads to reduced survival (p = 0.056).

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