Figure 1.
Comparison of two MRI scans over 10-year period.
The post-operative scan 10 years after DBS surgery shows an increase in size of the ventricles (millimeters) and widening of the Sylvian fissure (arrow). A: Preoperative scan for DBS targeting; B: Most recent scan.
Table 1.
Demographic and clinical characteristics of patients.
Table 2.
Comparison between initial and current thresholds.
Table 3.
Two time-point comparison of percentage change in brain atrophy measurements and lead measurements.
Figure 2.
Theoretical figure including atrophy which may play a role in delayed stimulation induced side effects.
Progressive 10%, 20%, 30%, and 40% atrophy with stimulation spread to other structures can be observed following columns to the right. DBS = Deep Brain Stimulation; Str = striatum; GPe = globus pallidus externus; GPi = globus pallidus internus; IC = internal capsule; Th = thalamus; STN = subthalamic nucleus; Vim = ventralis intermedius nucleus; RN = red nucleus; SNR = substantia nigra pars reticulata. This figure is theoretical and shows how atrophy may potentially affect lead location and stimulation fields.