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Table 1.

Subject characteristics by glucose and fasting status.

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Table 1 Expand

Figure 1.

Overall associations of S-Fructosamine with S-Glucose and B-HbA1c respectively.

All fasting states and all levels of glycemia included (All subjects).

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Figure 1 Expand

Figure 2.

Correlations of S-Fructosamine and B-HbA1c by fasting status, type 2 diabetes (new and diagnosed) and type 1 diabetes.

Fitted regression line with 95% confidence and prediction limits. Reference lines at fructosamine 2.5 mmol/L and at HbA1c 6.5% (48 mmol/mol).

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Figure 2 Expand

Figure 3.

Mean values of S-Fructosamine, S-Glucose and B-HbA1c over time by increase/reduction of S-Glucose at on average 290 days after the index examination.

Fasting subjects with new or diagnosed type 2 diabetes and with three simultaneous measurements of the biomarkers within one year are included.

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Figure 3 Expand

Figure 4.

Individual changes and correlations of S-Fructosamine, S-Glucose and B-HbA1c over time.

Fasting subjects with new or diagnosed type 2 diabetes and with three simultaneous measurements of the biomarkers within one year are included.

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Figure 4 Expand

Figure 5.

Mean values of fasting serum glucose and HbA1c by percentiles of S-Fructosamine with corresponding 1 standard deviation.

Sensitivity/Specificity at various fructosamine cut-off values for diagnosis of diabetes according to ADA criteria, 2.3 mmol/L (79%, 88%), 2.5 mmol/L (61%, 97%), 2.6 mmol/L (52%, 99%). Diagnostic discrimination of diabetes by S-Fructosamine using ROC analysis: AUC = 0.91 (fasting) AUC = 0.95 (non-fasting).

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Figure 5 Expand