Table 1.
Clinical characteristics of the study sample population.
Figure 1.
Linkage disequilibrium maps for SNPs genotyped in the region of the FNDC5 gene.
A. Shades of red demonstrate the strength of the pairwise linkage disequilibrium based on Dā and numbers represent the value of Dā expressed as a percentage. B. Shades of grey show the strength of the pairwise linkage disequilibrium based on r2 and numbers indicate the value of r2 expressed as a percentage.
Table 2.
Associations of FNDC5 SNPs with type 2 diabetes.
Figure 2.
Association between the SNP rs16835198 and fasting insulin levels in BMI-specific controls, under the additive genetic model.
The p value for interaction between rs16835198-BMI on fasting insulin was 0.003. A. Normal weight controls (BMI <25). B. Overweight/obesity controls (BMI ā„25).
Table 3.
Association analyses of rs16835198 with clinical characteristics in normal weight controls.
Table 4.
Association analyses of rs16835198 with clinical characteristics in overweight and obese controls.