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Figure 1.

Flowchart of studies included in meta-analysis. RCT, randomized controlled trial.

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Table 1.

Baseline characteristics of the head-to-head studies comparing ranibizumab with bevacizumab.

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Table 2.

Outcome data of randomized controlled trials included in the meta-analysis.

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Figure 2.

Risk ratio of thromboembolic events associated with intravitreal bevacizumab compared with ranibizumab.

Each study is shown by the point estimate of relative risk “risk ratio” (RR) - the size of the square is proportional to the weight of the study - and 95%confidence interval for the RR (lines extending from the squares); the pooled RR and 95%confidence interval are shown as a diamond.

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Table 3.

Risk ratio of systemic adverse events associated with intravitreal bevacizumab compared with ranibizumab.

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Table 4.

Summary of high-quality non-randomized studies comparing ranibizumab with bevacizumab.

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