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Figure 1.

Study flow showing patient recruitment and patients with available rapid plasma reagin (RPR) data during the 6 and 12 months of follow-up.

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Table 1.

Clinical characteristics of HIV-infected patients with early syphilis receiving 1 dose or 3 weekly doses of benzathine penicillin G.

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Figure 2.

Serological response rates in the 1-dose and 3-dose benzathine penicillin G groups at 6 months and 12 months of follow up.

A). Last-observed-carried-forward analysis; B). Per-protocol analysis.

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Table 2.

Factors associated with serological response in the patients who received 1 dose or 3 doses of benzathine penicillin G at 12 months of follow-up in univariate and multivariate analysis.

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Table 2 Expand

Figure 3.

Forest plot showing the serological response rates in different subgroups of patients receiving 1 or 3 doses of benzathine penicillin G at 12 months of follow-up.

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Figure 4.

Kaplan-Meier plot showing the time to treatment failure to 1- or 3-dose benzathine penicillin G regimen (Log rank test, P = 0.026).

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