Table 1.
Distribution for selected demographic and health characteristics comparing esophageal, stomach, and liver cancer cases with controls.
Figure 1.
Selected semi-Bayes stratum-specific associations.
Selected semi-Bayes stratum-specific associations between SNPs in MTHFR, MTR, MTRR, DNMT1, ALDH2, and upper GI cancer susceptibility, by plasma levels of micronutrients (folate, vitamin B12, and homocysteine) and environmental factors (smoking, alcohol drinking, H. pylori CagA status, HBsAg status, and plasma AFB1-albumin adduct levels). Semi-Bayes adjusted ORs (SBOR) and 95% posterior limits were under dominant genetic models, except for the SBOR relating ALDH2 rs671to esophageal cancer, where recessive genetic model was used. P* denotes P-value for homogeneity test.
Table 2.
Associations between SNPs of MTHFR, MTR, MTRR, DNMT1, and ALDH2 genes and cancers of the esophagus, stomach, and liver.
Table 3.
Associations between SNPs of MTHFR, MTR, MTRR, DNMT1, and ALDH2 genes and cancers of the esophagus, stomach, and liver –the comparison between results from single SNP model1 and joint SNPs model2.
Table 4.
Association between polygenetic risk score and cancers of the esophagus, stomach, and liver¶.