Figure 1.
Thresholding reaction of a DNA neuron.
Figure 2.
Irreversible DNA strand displacement.
Figure 3.
Abstract diagrams of implementation of a DNA neuron with AND logic.
Figure 4.
HEX and FAM fluorescent probes to detect the output spike “1/0” of DNA Neuron.
Figure 5.
Abstract diagrams of two DNA neurons executing XOR logic.
Figure 6.
Visual DSD simulations of AND logic gate with input signal “00”.
Figure 7.
Visual DSD simulations of AND logic gate with input signal “01”.
Figure 8.
Visual DSD simulations of AND logic gate with input signal “11”.
Figure 9.
Visual DSD simulations of XOR logic gate with input signal “00”.
Figure 10.
Visual DSD simulations of XOR logic gate with input signal “01”.
Figure 11.
Visual DSD simulations of XOR logic gate with input signal “11”.
Table 1.
The detailed amounts of involved DNA molecules in XOR logic gate.
Figure 12.
Fluorescence spectra of 6-FAM(FITC) and HEX.
Table 2.
All Oligonucleotides for “DNA neurons”.
Table 3.
Domains of “DNA neurons”.
Table 4.
Components samples.
Table 5.
Probes with Fluorophores.
Figure 13.
Fluoroscence data of DNA Neurons execute AND logic with input “00”.
The X-axis is cycling time of Real-time PCR, the time span of each cycle is 10 minutes, temperature of each cycle keeps in 24–25°C. The Y-axis is relative intensity of HEX (red curve) and FAM (blue curve).
Figure 14.
Fluoroscence data of DNA Neurons execute AND logic with input “01”.
The X-axis is cycling time of Real-time PCR, the time span of each cycle is 10 minutes, temperature of each cycle keeps in 24–25°C. The Y-axis is relative intensity of HEX (red curve) and FAM (blue curve).
Figure 15.
Fluoroscence data of DNA Neurons execute AND logic with input “11”.
The X-axis is cycling time of Real-time PCR, the time span of each cycle is 10 minutes, temperature of each cycle keeps in 24–25°C. The Y-axis is relative intensity of HEX (red curve) and FAM (blue curve).
Figure 16.
Fluoroscence data of DNA Neurons execute XOR logic with input “00”.
The X-axis is cycling time of Real-time PCR, the time span of each cycle is 10 minutes, temperature of each cycle keeps in 24–25°C. The Y-axis is relative intensity of HEX (red curve) and FAM (blue curve).
Figure 17.
Fluoroscence data of DNA Neurons execute XOR logic with input “01”.
The X-axis is cycling time of Real-time PCR, the time span of each cycle is 10 minutes, temperature of each cycle keeps in 24–25°C. The Y-axis is relative intensity of HEX (red curve) and FAM (blue curve).
Figure 18.
Fluoroscence data of DNA Neurons execute XOR logic with input “11”.
The X-axis is cycling time of Real-time PCR, the time span of each cycle is 10 minutes, temperature of each cycle keeps in 24–25°C. The Y-axis is relative intensity of HEX (red curve) and FAM (blue curve).