Table 1.
Demographics of Subject Groups.
Figure 1.
Comparison of platelet aggregometry measurements in different pathological groups and healthy control.
Platelet aggregation measurements induced by ADP, ASPI and Collagen agonists are shown in the different pathological groups and healthy control. Aggregometry measurements are expressed as area under the curve (AUC, arbitrary units). Significant differences between the groups are indicated by p-values, as assessed by Bonferroni post-hoc analysis.
Figure 2.
Comparison of whole blood parameters in different pathological groups and healthy control.
Platelet count, white cell count, haemoglobin and haematocrit measurements are shown in different pathological groups and healthy control. Significant differences between the groups are indicated by p-values, as assessed by Bonferroni post-hoc analysis.
Table 2.
Comparison of SIRS/Uncomplicated sepsis and severe sepsis/septic shock.
Figure 3.
Receiver operating characteristics for discrimination between SIRS/Uncomplicated Sepsis and Severe Sepsis/Septic Shock groups.
Receiver operating characteristics are shown for platelet aggregometry measurements, whole blood parameters and sepsis-related organ failure assessment (SOFA) score as a discriminator between patients with and without organ dysfunction.
Table 3.
Receiver Operating Characteristics for the Diagnosis of Severe Sepsis.
Table 4.
Sensitivity and Specificity for the Diagnosis of Severe Sepsis.
Figure 4.
Receiver operating characteristics for discrimination between survivors and non-survivors at 28 days.
Receiver operating characteristics are shown for platelet aggregometry measurements and whole blood parameters for the discrimination between 28-day mortality and survival.
Table 5.
Characteristics of Survivors and Non-Survivors in Relation to Platelet Aggregation and Whole Blood Parameters.
Table 6.
Receiver Operating Characteristics for Survivors and Non-Survivors for Platelet Aggregation and Whole Blood Parameters.
Figure 5.
Effect of treatment and disease progression on platelet aggregation and whole blood parameters.
Platelet aggregation and whole blood parameters were measured at baseline, 6 hours and 24 hours are shown. *Significant result (P<0.05), two-sample t-test.
Table 7.
Pearson's Correlations of Whole Blood Aggregometry versus Whole Blood Parameters.