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Table 1.

Lesion distribution and chronic changes in brain lesion size on T2-weighted images.

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Table 2.

Lesion distribution and chronic changes in signal intensity of T1-weighted images.

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Figure 1.

Most acute brain lesions in the white matter (Aa, Ba) showed a decrease in size and/or faded.

Most remnant hyperintense lesions in hemispheric white matter on T2/FLAIR images were irregular in shape and located mainly in the subcortical/deep white matter (Ab, Bb). Acute hyperintense lesions in the bilateral hypothalamus (Ca) and around the fourth ventricle and cerebellum (Da, Ea), basal ganglia, and cortical/subcortical (Fa) on T2/FLAIR images resolved completely on follow-up brain MRI (Cb, Db, Eb, Fb).

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Figure 2.

Chronic cystic changes of brain lesions on MRI.

At the time of an acute brain attack, brain MRI showed multiple T2-hyperintense lesions with subtle T1 hypointensity in the frontal white matter (Aa), corticospinal tract (Ba, Ca), occipital white matter (Da) and corpus callosum (Ea). On follow-up MRI, all T2 hyperintense lesions were markedly decreased in size but revealed focal T1-hypointensity with cystic changes (Ab, Bb, Cb, Db, Eb).

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Figure 3.

Focal atrophy on follow-up brain MRI.

Acute lesions in crus cerebri (Aa) and corpus callosum (Ba) revealed focal atrophy with remnant T2-hyperintense lesions on chronic MRI (Ab, Bb).

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