Figure 1.
Neural structural changes with age in Group 1.
(A) shows FA changes. Note that the skeletonized results are “thickened” to help visualization. Left SLF-IFC/Prg, left superior longitudinal fasciculus underlying the inferior frontal cortex and precentral gyrus; Left SLF-TP, left superior longitudinal fasciculus underlying the temporal-parietal association cortex; Left and right IFOF-IFC, left and right inferior fronto-occipital fasciculus underlying the inferior frontal cortex; Right FM-MeFC, right forceps minor underlying the medial frontal cortex; Left bCC, left body of corpus callosum. (B) shows cortical thickness changes. The colored blobs (blue for cortical thickness, red for FA) indicate brain areas that correlated negatively with age. Left IFC, left inferior frontal cortex; Left Prg, left precentral gyrus. No positive correlations were found.
Table 1.
Brain regions showing significant correlations with age in group one.
Figure 2.
Consistency among WM/GM and between WM and GM matter changes in Group 1.
The correlation matrix among all ROIs, including both GM and WM matter, are given.
Figure 3.
Linear regression fit results.
(A) shows fitting result when using grand-averaged cortical thickness as the dependent variable in Group 1. (B) shows fitting result when using age as the dependent variable in Group 1. (C) Re-examination of Group 1's ROI in Group 2's data. Age is the dependent variable. Note that the red line is the linear fit result, whereas the green lines are the confidence internal (95%). For all three panels, the x-axis corresponds to the actual age or cortical thickness, whereas the y-axis corresponds to the age or cortical thickness produced by the regression model.