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Figure 1.

Sephadex LH-20 column chromatography for purification and fractionation of tannins from C. tagal leaves.

Subfraction 8 (F8) and Subfraction 9 (F9) were further fractionated into F8-1 to F8-4 and F9-1 to F9-3, respectively.

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Figure 1 Expand

Figure 2.

Structural characterization of purified tannins (Fp) from C. tagal leaves.

Analyzed by (a) 13C-NMR, (b) reversed-phase HPLC-ESI-MS, (c) normal-phase HPLC-ESI-MS and (d) MALDI-TOF MS.

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Figure 2 Expand

Figure 3.

Reflectron mode MALDI-TOF mass spectra for tannin subfraction F4 (a) to F9 (f).

Degree of polymerization (DP) of the predominant polymers and largest polymer in each mass spectrum of subfraction are labeled.

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Figure 3 Expand

Figure 4.

Linear mode MALDI-TOF mass spectra for tannin subfraction F8 (a).

F8-1 (b) to F8-4 (e) were obtained by the further re-fractionation of F8. Degree of polymerization (DP) of the predominant polymers and largest polymer in each mass spectrum of subfraction are labeled.

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Figure 4 Expand

Figure 5.

Linear mode MALDI-TOF mass spectra for tannin subfraction F9 (a).

F9-1 (b) to F9-3 (d) were obtained by the further re-fractionation of F9. Degree of polymerization (DP) of the predominant polymers and largest polymer in each mass spectrum of subfraction are labeled.

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Figure 5 Expand

Table 1.

Mean degree of polymerization (mDP) and antioxidant activities of each subfraction obtained by fractionation of proanthocyanidins from C. tagal leaves.

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Table 1 Expand

Figure 6.

Regression analysis for mean degree of polymerization (mDP) and antioxidant activity.

(a) EC50/DPPH value and (b) FRAP value correlated with mDP for each proanthocyanidin subfraction from C. tagal leaves.

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Figure 6 Expand