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Figure 1.

Photographs of the Pathogon (A) and Tru-D (B) devices.

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Figure 2.

The effect of pathogen concentration on the efficacy of the UV-C devices.

The log10CFU reduction/cm2 of two strains of C. difficile spores, MRSA, and VRE inoculated onto carriers. Carriers contained either >5, ≤5 and >3, or ≤3 log10CFU of each pathogen. The carriers were irradiated for 41 minutes at a distance of 4 feet from the Tru-D (2A) or Pathogon (2B) device. The means of the data from experiments conducted in triplicate are presented. Error bars indicate standard error.

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Figure 3.

The effect of organic load on the efficacy of the UV-C devices.

The log10CFU reduction/cm2 of C. difficile spores, MRSA, and VRE suspended in phosphate-buffered saline (PBS), light organic load (5% fetal calf serum), or heavy organic load (5% fetal calf serum, 5% tryptone). Carriers contained 6 log10CFU of each pathogen. The carriers were irradiated for 41 minutes at a distance of 4 feet from the Tru-D or Pathogon device. The means of the data from experiments conducted in triplicate are presented. Error bars indicate standard error.

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Figure 4.

The effect of distance and indirect irradiation on the efficacy of the UV-C devices.

The log10CFU reduction/cm2 of C.difficile spores, MRSA, and VRE at increasing distances and shaded from the direct field of radiation delivered by the UV-C device. Carriers contained 6 log10CFU of each pathogen. The carriers were irradiated for 41 minutes at a distance of 6 in, 4 feet, 4 feet shaded, and 10 ft from the Tru-D or Pathogon device. The means of the data from experiments conducted in triplicate are presented. Error bars indicate standard error.

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Figure 4 Expand

Figure 5.

The effect of radiant dose on the efficacy of the UV-C devices.

The log10CFU reduction/cm2 of C.difficile spores, MRSA, and VRE after receiving increasing timed doses of irradiation delivered by the UV-C devices. Carriers contained 6 log10CFU of each pathogen. The carriers were irradiated for 10, 20, 40 minutes at a distance of 4 feet from the Tru-D or Pathogon device. The means of the data from experiments conducted in triplicate are presented. Error bars indicate standard error.

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