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Figure 1.

Flow diagram of trial identification and selection.

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Table 1.

Baseline characteristics of studies included in the meta-analysis*.

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Figure 2.

Forest plot of overall incidence of severe (grade 3 or 4) mucositis.

Squares to the left of the vertical line indicate that low level laser therapy reduces mucositis. Horizontal lines through the squares represent 95% confidence intervals (CIs). The size of the squares reflects each study's relative weight, and the diamond represents the aggregate risk ratio and 95% CI.

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Table 2.

Summary of outcomes of low level laser therapy as compared to placebo/no treatment.

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Table 2 Expand

Table 3.

Effect of low level laser therapy as compared to placebo/no therapy on overall incidence of severe (grade 3 or 4) mucositis stratified by patient, laser and risk of bias characteristics.

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Table 3 Expand

Figure 3.

Funnel plot “trim and fill” technique assessing publication bias for overall incidence of severe mucositis.

The x-axis represents the risk ratio for the effect of low level laser therapy and the y-axis represents the inverse of the variance of the effect. Estimated number of missing studies on right side = 4.

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