Figure 1.
Projection fibers, in top view and left view.
Figure 2.
Association fibers in top view and left view.
Figure 3.
Commissural fibers in top view and left view.
Figure 4.
Brainstem fibers in top view and left view.
Figure 5.
Short range WM regions in top and left view.
Figure 6.
A coronal slice of the WM atlas.
Overlaid on a T1-W template (left) and an FA color map (right). AT-WM = adjacent thalamus, BCC = body of corpus callosum, CgC = superior cingulum bundle, CgH = perihippocampal cingulum tract, CP = cerebral peduncle, CST = corticospinal tract, DPCR = dorsal posterior corona radiata, EC = external capsule, FX = fornix, MCP = middle cerebellar peduncle, SCR = superior corona radiata, SLF = superior longitudinal fasciculus, SS = sagittal striatum, ST = stria terminalus.
Figure 7.
A sagittal slice of the WM atlas.
Overlaid on a T1-W template. AC = anterior commissure, AT-WM = adjacent thalamus, AA-WM = adjacent amygdala, ALIC = anterior limb of the internal capsule, BCC = body of corpus callosum, CgH = perihippocampal cingulum tract, CP = cerebral peduncle, CST = corticospinal tract, DPCR = dorsal posterior corona radiata, DPF = dorsal prefrontal, FX = fornix, GCC = genu of corpus callosum, ICP = inferior cerebellar peduncle, MB-WM = midbrain, MCP = middle cerebellar peduncle, OC = olivocerebellar tract, PLIC = posterior limb of the internal capsule, SCC = splenium of corpus callosum, ST = stria terminalis, UNC = uncinate fasciculus.
Figure 8.
An axial slice of the WM atlas.
Overlaid on a T1-W template (left) and an FA color map (right). ACg-WM = anterior cingulum, ALIC = anterior limb of the internal capsule, CgC = superior cingulum bundle, CgH = perihippocampal cingulum tract, EC = external capsule, FX = fornix, GCC = genu of corpus callosum, IFG-WM = inferior frontal gyrus WM, MTG-WM = middle temporal gyrus WM, PLIC = posterior limb of the internal capsule, PTR = posterior thalamic radiation, RLIC = retrolenticular limb of the internal capsule, SCC = splenium of corpus callosum, SCR = superior corona radiata, SLF = superior longitudinal fasciculus, ST = stria terminalus, STG-WM = superior temporal gyrus WM, TAP = tapetum.
Figure 9.
Top: FA maps of select slices of template (anterior on left, posterior on right) with atlas ROIs overlaid. Bottom: Color FA map of matching slices, showing delineation between tracts. Arrows indicate the division between the SCR (a) and the DPCR (b), and the directional (color) changes that guided the decision of where to put this boundary.
Figure 10.
(A) Superior 3D surface rendered view of atlas. (B) Left 3D surface rendered view of atlas. The superior cingulum bundle (CgC) and many peripheral WM tracts are pointed out. IFG-WM = inferior frontal gyrus WM, SLF = superior longitudinal fasciculus, MTG-WM = middle temporal gyrus WM, DPCR = dorsal posterior corona radiata.
Figure 11.
WM atlas and digital Paxinos atlas of GM regions overlaid on UWRMAC-DTI271 template FA map.
Figure 12.
Registering to a different template.
Two representative coronal slices of the atlas in its default space (A) and after registering with nearest-neighbor interpolation to a template made from a smaller number of young rhesus macaques (B), which were not a part of the original DTI template used to draw the atlas. White matter coverage is equally good in the registered atlas, qualitatively.
Figure 13.
Image showing overlap between manual (blue) and automatic (red) methods of defining tracts.
Manual definitions of the corpus callosum and ALIC (anterior limb of the internal capsule (A, C) and the PTR (posterior thalamic radiation) (B, D) were drawn on the different template and compared to automatically defined regions. Overlap agreement appears in purple. Slices were selected that illustrated areas where the two segmentation methods disagreed.
Table 1.
Agreement between automated and hand segmentation in the BCC (body of corpus callosum), PTR (posterior thalamic radiation) right, left, and bilateral, and ALIC (anterior limb of the internal capsule) right, left, and bilateral.
Figure 14.
Multiple slices of atlas overlaid on T1-W template beside directional FA color image, axial view.
Figure 15.
Multiple slices of atlas overlaid on T1-W template beside directional FA color image, coronal view.
Figure 16.
Multiple slices of atlas overlaid on T1-W template beside directional FA color image, sagittal view.