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Table 1.

Comparison of demographic and clinical characteristics of the patients evaluated with OAS and GS. Statistical significance is indicated (P).

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Table 2.

Skin test results to inhalant and food allergens in patients with OAS and GS. Statistical significance is indicated (P).

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Table 2 Expand

Figure 1.

ELISA results to allergens (Mal d 1, Mal d 2, rMal d 3, rMal d 4, rPru p 3, rBet v 1 and Pho d 2) in sera from patients with OAS (N = 35) and GS (N = 46) and a control group with tolerance to apple (N = 25).

(A) Results are expressed as individual O.D. values and median represented as a dotted line. (B) Results are expressed as the percentage of positive cases. (*p<0.05) represents a significant difference compared to healthy controls.

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Table 3.

Percentages of ELISA positive cases combining allergens from LTP and profilin family in patients allergic to apple with OAS or GS.

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Table 3 Expand

Figure 2.

ELISA Inhibition results using rMal d 3 and rPru p 3 in the solid phase for a representative case from Group 1 with GS (A); Mal d 4 and Pho d 2 in a representative case from Group 2 with OAS (B) and a case with GS (C); and Mal d 3 and Pho d 2 in a representative case from Group 3 with OAS (D) and a case with GS (E).

Sera were preincubated with decreasing concentrations (20–0.2 µg/ml) of rMal d 3, rMal d 4, rPru p 3, and Pho d 2, before they were added to the solid phase. Results are expressed as percentage inhibition.

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Figure 3.

ELISA Inhibition results using in the solid phase rMal d 1 (A) and rBet v 1 (B) with different concentrations (20–0.2 µg/ml) of rMal d 1, Mal d 2, rMal d 3, rMal d 4 and rBet v 1 in a representative OAS patient with high recognition of Betv1.

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Figure 3 Expand