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Table 1.

Demographic and health characteristics.

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Figure 1.

Group differences in cognitive domain composite scores of the Montreal Cognitive Assessment.

The bar chart in figure 1 displays the average points scored by the patient and control group for each of the cognitive domains of the Montreal Cognitive Assessment (MoCA). The group differences were assessed using the non-parametric Mann-Whitney-U test with respective p-values showing a significantly (p≤.001) poorer performance of the patient group in the domains of executive functions, episodic memory and language. Notes. *Executive: Trail Making Test (TMT) B, verbal abstraction, digit span backwards, phonemic word fluency; Visuospatial: cube copying, clock drawing; Memory: immediate and delayed word recall; Attention: digit span forwards, letter cancelation, number subtraction; Language: sentence repetition, animal naming; Orientation: temporal and spatial orientation. Group differences were assessed using the Mann-Whitney-U test with a significance level of p≤.001.

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Table 2.

Neuropsychological test results.

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Table 2 Expand

Figure 2.

ROC curves for the cognitive screening tests Montreal Cognitive Assessment and Mini-Mental State Examination.

The receiver operating characteristics curves for the Montreal Cognitive Assessment (MoCA) and the Mini-Mental State Examination (MMSE) illustrate the discriminative capacity of each of the screening tests, displaying their individual sensitivity, specificity and area under the curve (AUC). The MoCA shows good levels of sensitivity and specificity, as well as an overall greater AUC than the MMSE, while the MMSE presents a high specificity and relatively low sensitivity. Notes. MoCA = Montreal Cognitive Assessment; MMSE = Mini-Mental State Examination; AUC = Area under the curve.

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Table 3.

Criterion (cut-off) values and coordinates of the ROC curves of MoCA and MMSE.

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Table 3 Expand