Figure 1.
Depiction of voxel positioning for MRS on a background of a T1 individual structural image.
Figure 2.
DMN identified in the group analysis of the 20 subjects; the DMN was picked by visual inspection, comprising medial prefrontal cortex (MPfC), anterior and posterior cingulate cortices (ACC and PCC), precuneus and lateral parietal inferior gyri (LPIG).
Figure 3.
Voxel-wise statistical maps with the inclusion of the GABA ratio measured in the PCC and generated by the dual regression analysis of the DMN.
Significant voxels thresholded at p<0.05 (corrected). The point of lowest p value (p = 0.0002) was located in MNI coordinates x = 26, y = 10, z = 4. The background image is the MNI152 T1 (2 mm) template.
Table 1.
MNI coordinates (2 mm template) of clusters with minimal P values of linear relationship between GABA ratio and z–values in the DMN.
Figure 4.
Mean z–values extracted from the left putamen in relation to GABA ratio in the PCC.