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Figure 1.

Flow diagram for ROI selection.

The T1WI anatomic imaging, ADC and Tmax maps were displayed simultaneously when selecting the ROIs manually on anatomic T1WI imaging. Three ROIs were drawn at different slices for each area. The ROIs were than applied to the resting-state BOLD EPI map to get the ALFF value.

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Figure 1 Expand

Table 1.

Demographic Data and Relative ALFF value of the stroke subjects.

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Figure 2.

Illustrative resting fMRI, DWI and Tmax maps in three cases.

The bright regions in DWI represented core of infarction and the defects in Tmax maps include both infarct core and penumbra area. ALFF indicates amplitude of low frequency fluctuation; fALFF: fractional ALFF; ReHo: regional homogeneity; StDev: Standard Deviation maps; DWI: diffusion-weighted image; Tmax: time-to-maximum; s: second. The scale bars for the fMRI represent Z score.

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Figure 3.

Scatter plots showing the relationships between relative ALFF and time after stroke in (A) Infarct, (B) Ipsilateral normal and (C) Penumbra zones.

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Figure 3 Expand