Figure 1.
FA status in TLE patients before surgery.
Left TLE in the left (panel A) and right TLE in the right (panel B). Post-surgery changes are displayed for left (panel C) and right (panel D) ATL patients. Slice positions are displayed in the upper left corner. The six slices displayed in each panel are located in MNI space x = [−40 −27 −8 +8 +28 +40]. Abbreviations indicate SLF = superior longitudinal fasciculus, and SCR = superior corona radiata.
Figure 2.
Amount of FA change for each tract pre-to-post surgery.
Black lines represent average values in healthy controls. Abbreviations: Fx = body of fornix; Fx/ST = fornix (stra terminalis); CGH = cingulate of hippocampus (parahippocampal); CGC = cingulate of cingulate gyrus; GCC = genu of corpus callosum; BCC = body of corpus callosum; SCC = splenium of corpus callosum; SFO-superior fronto-occipital fasciculus; SLF = superior longitudinal fasciculus; UNC = uncinate fasciculus; IFO = inferior fronto-occipital fasciculus; SS = sagittal stratum; EC = external capsule; ALIC = anterior limb of internal capsule; PLIC = posterior limb of internal capsule; ACR = anterior corona radiata; SCR = superior corona radiata; PTR = posterior thalamic radiation.
Figure 3.
Overlap of longitudinal FA increase and cross-sectional post-surgery comparison with controls.
A similar area in the ipsilateral SCR is observed to increase FA in LATL and RATL patients reaching values beyond those found in normal controls.
Figure 4.
FA change with respect to post-surgery interval.
Panel A shows FA change inversely related to post-surgery time interval in the genu of corpus callosum for LATL patients. Panel B shows raw FA values from the 12 LATL patients before (time 0) and after surgery in the same cluster shown in Panel A.
Figure 5.
Postoperative relationship between phonemic fluency and FA values.
The four clusters that increased FA in the two groups are shown in the four panels (blue = LATL group; red = RATL group). The regression line is placed for the significant correlation found in the right superior longitudinal fasciculus.