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Table 1.

Baseline characteristics of the study population.

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Table 2.

Parameters at baseline.

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Figure 1.

Changes in perfused capillary density following infusions of dobutamine (median 60 minutes), enoximone (median 85 minutes), and norepinephrine (median 75 minutes) at the individual patient level.

↑, increase of parameter following inotropic therapy in terms of percentage relative to baseline. The reference value of perfused capillary density is indicated by the red dashed line (ie, 10.3 mm.mm−2). Values greater than this reference are to be considered as preserved capillary density, values below or equal to this reference reflect impaired capillary density [5].

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Table 3.

The effects of infusions of dobutamine (median 60 minutes), enoximone (median 85 minutes), and norepinephrine (median 75 minutes) on parameters of macro- and microcirculation.

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Table 4.

Correlations between changes in pooled global hemodynamic and microcirculatory parameters.

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Figure 2.

Thirty-day mortality according to final perfused capillary density.

In the subgroup of patients (n = 18) with low perfused capillary density (ie, ≤10.3 mm.mm−2), 13 patients died, whereas in the subgroup of patients (n = 12) with preserved capillary density (ie, >10.3 mm.mm−2) 2 patients died (p = 0.003).

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