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Figure 1.

Flowchart for the inclusion of valproate-treated patients with epilepsy.

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Table 1.

Clinical characteristics of patients with epilepsy who received valproate treatment.

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Table 2.

Logistic regression model for metabolic syndrome and its components in patients treated with valproate compared to control subjects.

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Table 3.

Characteristics of subjects receiving valproate monotherapy with and without metabolic syndrome.

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Table 4.

Anthropometric and laboratory data in the patients and control subjects.

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Figure 2.

Receiver operating characteristic (ROC) curves of the homeostasis model assessment-estimated insulin resistance (HOMA-IR) and body mass index (BMI) values in control subjects.

BMI and HOMA-IR curves were obtained by logistic regression to determine the probability of metabolic syndrome (MS) in control subjects. AUC, area under the curve.

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Figure 3.

Receiver operating characteristic (ROC) curves of the homeostasis model assessment-estimated insulin resistance (HOMA-IR) and body mass index (BMI) values in valproate (VPA)-treated patients.

BMI and HOMA-IR curves were obtained by logistic regression to determine the probability of metabolic syndrome (MS) in patients treated with VPA. AUC, area under the curve.

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Figure 3 Expand