Table 1.
Clinicopathological features of colorectal neoplasms.
Table 2.
Clinicopathological and molecular characteristics among different macroscopic subtypes of CRNs.
Table 3.
Molecular alterations in relation to clinicopathological findings (multivariate analysis).
Figure 1.
Macroscopic subtypes in colorectal tumorigenesis.
Precursor lesions can progress to cancer through the acquisition of epigenetic or genetic changes. Tumors from each subtype exhibit different characteristics, including their underlying molecular and genetic defects. However, whether small flat-elevated neoplasms can progress to other subtypes of CRNs remains unknown. PN, Polypoid neoplasm; LST-G, granular type laterally spreading tumor; LST-NG, non-granular type laterally spreading tumor; S-FN, small flat-elevated neoplasm; DN, depressed neoplasm.